microRNA discovery using Illumina high throughput sequencing

The study of microRNA (miRNA) is growing rapidly as researchers discover new miRNAs and uncover the importance of these small regulatory elements linked to a wide range of biological functions.  The miRBase sequence database¹ is the primary public repository for newly discovered miRNAs and the number of miRBase entries has grown rapidly from a mere 218 in 2002 to almost 10,000 in the latest version, suggesting the existence of many more miRNAs yet to be discovered.

MicroRNA sequencing is a new method and a powerful tool to identify and quantitatively decode the entire population of microRNAs in your sample. LC Sciences now provides a microRNA discovery service using the Illumina high-throughput sequencing technology which enables comprehensive coverage, highly sensitive and specific discovery and profiling of all forms of microRNAs in your sample. Profile microRNA in any species - there is no need for probes based on prior sequence or secondary structure information. Profiling is transcriptome-wide, you can investigate all microRNAs, of any size, known and unknown, in your sample.. Achieve digital transcript expression analysis – Accurate quantitation of expression levels over 5 orders of magnitude of transcript abundance. Detect rare transcripts and transcript variants, such as single nucleotide mutations (SNP).They also provides the comprehensive data analysis facility.